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Book Title: Treating and Preventing Adolescent Mental Health Disorders
> pp. [xxxv]-[xxxix]
UNDEFINED: AUTHORS
Treating and Preventing Adolescent Mental Health Disorders
Print ISBN 9780195173642, 2005
pp. [xxxv]-[xxxix]
tinctions within the prevention category are given below.
Universal mental health prevention interventions are defined as efforts that are beneficial to a whole population or group. They are targeted to the general public or a whole population group that has not been designated or identified as being at risk for the disorder being prevented. The goal at this level is the reduction of the occurrence of new cases of the disorder.
Selective mental health prevention interventions are defined as those efforts that target individuals or a subgroup of the population whose risk of developing the mental health disorder is significantly higher than average. The risk may be immediate or lifelong. Biological, psychological, or social risk factors associated with or related to the specific mental health disorder are used to identify the individual or group level risk.
Indicated prevention interventions are defined as those efforts that target high-risk individuals who are identified as having minimal but detectable signs or symptoms that predict the mental disorder or biological markers indicating predisposition to the disorder. For example, individuals who have some symptoms of major depressive disorder but do not yet meet criteria for the disorder would fall into this group. Although this definition includes early intervention, it excludes individuals whose signs and symptoms meet diagnostic criteria for the disorder. In the Institute of Medicine ( 1994) definitions, interventions with individuals who meet diagnostic criteria would be considered treatment.
Definition of Additional Prevention Terms
A further clarification of potentially confusing terms used within the prevention field was presented in the 1999 Surgeon General report on mental health (U.S. Department of Health and Human Services, 1999). In this report, first (initial) onset was defined as the initial point in time when an individual's mental health problems meet the full criteria for a diagnosis of a mental disorder. Risk factors were defined as those variables that, if present, make it more likely that a given individual, compared to someone selected at random from the general population, will develop a disorder. Although risk factors precede
the first onset of a disorder, they may change in response to development or environmental stressors. Protective factors include factors that improve an individual's response to an environmental hazard and result in an adaptive outcome. These protective factors can be found within the individual or within the family or community. They do not necessarily lead to normal development in the absence of risk factors, but they may make an appreciable difference in the influence exerted by risk factors. We have adopted these clarifications offered in the Surgeon General's (1999) report here. It is also important to distinguish between the risk of onset and the risk of relapse of a disorder. This is important because the risks for onset, or protection from onset, of a disorder are likely to be somewhat different from the risks involved in relapse, or protection from relapse, of a previously diagnosed condition. In this book, the prevention of relapse is included in chapters on treatment, whereas the prevention of onset of a disorder is discussed in chapters on prevention.
Pharmacological Intervention in Adolescence
Psychopharmacological interventions in children and adolescents are now common. In part because of the availability of selective serotonin reuptake inhibitors (SSRIs) as well as increased recognition of depression and treatment seeking, there has been a substantial increase in antidepressant prescriptions for children and adolescents (Ofson, Marcus, Weissman, & Jensen, 2002; Zito et al., 2003). The U.S. Food and Drug Administration (FDA) has now granted approval for the SSRIs fluvoxamine, sertraline, and fluoxetine for the treatment of obsessive-compulsive disorder in children and adolescents, and for fluoxetine for the treatment of major depressive disorder in patients 8 years of age or older. In 2002, approximately 10.8 million total prescriptions were dispensed for the newer antidepressants among those 17 years and younger (Holden, 2004). About half of children and adolescents treated for depression in the United States receive medication (Olfson et al., 2003). Similarly, stimulant prescriptions for attention-deficit hyperactive disorder have also been on
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the rise, with one study finding that 9.5% of children 6 to 14 years of age were receiv-ing such medication (Rushton & Whitmire, 2001). The use of psychotropic medication in youth has recently come under scrutiny because of a possible link between use of antidepressants and increased suicidality. On the basis of an inspection of safety data, in late 2003 the U.K. drug regulatory agency recommended against the use of all SSRIs, except fluoxetine, in treating depression among youth under age 18 (Goode, 2003). After examining reports by pharmaceutical companies of their drug trials and listening to testimony at a public hearing on the issue, the FDA issued a public health advisory on antidepressants in March 2004 (FDA Public Health Advisory, 2004; Harris, 2004). In their statement, the FDA asked manufacturers of 10 specific SSRIs to place detailed information about the drugs' side effects prominently on their labels, and to specifically recommend close observation of adult and pediatric patients for the worsening of depression and the development and/or worsening of suicidality. In September 2004, an FDA advisory committee met to further review the issue of suicide and SSRIs. The committee concluded that there was evidence for an increased risk of suicidality in pediatric patients, and that this risk applied to all drugs examined (Prozac, Zoloft, Remeron, Paxil, Effexor, Celexa, Wellbutrin, Luvox, and Serzone). On the basis of this risk, the advisory committee recommended that any warning related to an increased risk of suicidality in pediatric patients should be applied to all antidepressant drugs, including older antidepressants and medications that have not been tested in pediatric populations. However, the committee also recommended that these medications not be removed from the market in the United States because access to these therapies was important for those who could benefit from them. The FDA subsequently announced that it generally supported these recommendations and was working on new warning labels for all antidepressants. The chapters on mood disorders and suicide in this volume carefully consider the risks vs. benefits of antidepressant use in youth.
Positive Youth Development
In addition to our focus on the treatment and prevention of mental disorders in adolescence, this book adds another important perspective on adolescent mental health: positive youth development. Rather than focusing on symptomatology, disorders, or problems, positive youth development deals with each youth's unique talents, strengths, interests, and future potential. There are two major reasons why positive youth development is an essential aspect of adolescent mental health and is therefore included prominently in this book. The first is our emphasis on prevention. Preventive programs that target nondisordered populations (e.g., universal mental health prevention) often are oriented toward building strengths, such as social competencies, rather than directly addressing negative behaviors, emotions, or symptoms. A full understanding of the range of positive virtues and strengths and their relation to competencies, well-being, and the development of disorders, problems, and symptoms is therefore necessary to successfully design preventive efforts and evaluate their effectiveness. The second reason that positive youth development features prominently in this book is our view that adolescent mental health is much more than symptoms and disorders. As parents, teachers, and mental health professionals, our goals are to prepare young people for the demands of life. Having no symptoms or disorder is not likely to be sufficient to insure that adolescents thrive and form positive connections to the larger world as they transition into adulthood. Successful achievement of positive mental health, satisfaction with life, and adjustment to society may have more to do with certain positive characteristics such as curiosity, persistence, gratitude, hope, and humor than with the absence of symptoms. Indeed, research has shown that positive external (i.e., family support and adult mentors) and internal (commitment to learning, positive values, and sense of purpose) factors in youth are associated with academic success, the helping of others, leadership, and decreased problems (Benson, Leffert, Scales, & Blyth, 1998; Leffert et al., 1998; Scales, Benson,
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Leffert, & Blyth, 2000; see Chapter 26 for more details). The emphasis on positive youth development is complementary to the treatment and prevention of disorders. Adolescents will obviously continue to experience problems and disorders that need attention and treatment. Disorders themselves may be preventable or reducible through development of strengths and virtues. But by also addressing positive values and strengths, in disordered and nondisordered youth, we believe we can maximize the chances that successful lives will ensue.
The Settings for Interventions in Adolescence
The Mental Health and Substance Abuse Treatment System
Each of the chapters on disorders in this book identifies treatments and prevention programs that have been found to work. What has become increasingly clear is that the development of such efficacious treatment is only a first step toward improving public health. It is also essential to take into account the settings in which the interventions occur. Currently in the United States, there are significant challenges to providing quality care for youth and their families within the mental health and substance abuse treatment systems that serve these populations. The severity of these challenges are highlighted in two chapters on service delivery systems for adolescents, one by Myers and McLellan regarding the substance abuse service delivery system in the United States, and one by Hoagwood on the mental health service delivery system. Both of these chapters document systemic barriers to implementing evidence-based treatments in our existing service delivery system. One of the primary barriers, reviewed in greater detail in Chapters 28 and 29, is service fragmentation—that is, the fact that treatment of children and adolescents is performed by at least six separate systems: specialty mental health, primary health care, child welfare, education, juvenile justice, and substance abuse. Other barriers include poor access and use of services among minorities, lack of sustained family involvement, and fiscal dis
incentives under managed care. Thus, a research agenda for the future would not be complete without an understanding of and improvement in the relevant service delivery systems.
Schools have long been recognized as an important context for adolescent mental health development and service delivery. In fact, schools have been described as the de facto mental health service delivery system for children and adolescents, with between 70% and 80% of those that receive any form of mental health service obtaining such services from within the school setting (Burns et al., 1995). Higher prevalence rates of mental disorders and higher rates of comorbidity have been found among children and adolescents receiving services within the special education services of school than in specialty mental health clinics or in substance abuse clinics (Garland et al., 2001). More than any other setting, schools provide access to adolescents for assessment and intervention. Student functioning, at least in terms of cognitive functioning needed for successful academic achievement, is tracked regularly, and behavior is assessed by multiple observers (teachers). At the first sign of problems, interventions could be initiated, rather than waiting until serious disorders develop and the adolescent is brought to a psychiatrist. Preventive interventions designed to target large populations of adolescents are particularly well suited for the school setting. Unfortunately, as described in Chapter 31 on adolescent mental health and schools, the current state of mental health services in school is poor. There is wide variability across states and between urban and rural locations in the availability of mental health services in schools, with only about half of high schools having on-site mental health services (Brener, Martindale, & Weist, 2001; Slade, 2003). Increasing the availability and quality of school-based services for the assessment, treatment, and prevention of adolescent mental health problems is therefore a central component of any plan for improving the lives of adolescents.
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A particular component of the service delivery system, primary care medical practice, merits special attention in regard to adolescent mental health. In a typical year, over 70% of young people visit a primary care physician (Wells, Kataoka, & Asarnow, 2001). Primary care physicians typically serve as the gateway to obtaining specialist care, including mental health services. However, primary care physicians are typically poorly trained in psychiatry and psychology. Results of a national survey of primary care residency programs revealed that the average program devotes about 100 hours over the course of 3 years of residency to psychiatry training, with little or none of this specifically in child and adolescent psychiatry (Chin, Guillermo, Prakken, & Eisendrath, 2000). Compounding the problem is the fact that primary care physicians have enormous time constraints, especially since the advent of managed care and health maintenance organizations. These time constraints make it difficult for primary care physicians to adequately diagnose mental health problems. A recent study of over 20,000 youths visiting a primary care physician revealed that such physicians identified mood or anxiety syndromes at a rate substantially lower than that found in epidemiological studies (Wren, Scholle, Heo, & Comer, 2003). Inaccurate or missed diagnoses will lead to inadequate treatment. Chapter 30 addresses in more detail the issues of identification and treatment of adolescent mental health problems in primary care settings. A unique aspect of this chapter is the presentation of a new study, commissioned by the Annenberg Adolescent Mental Health Initiative, which evaluates the practices of primary care physicians who treat large numbers of adolescents in the United States. This study found that physicians are concerned about the mental health of their adolescent patients and regard mental health as an important responsibility. In addition, the vast majority of primary care providers believe in the efficacy of treatment for mental disorders. However, primary care providers report low confidence in their ability to diagnose mental health problems, and only half employ any screening technique at all to detect
mental health problems in their adolescent patients. These results suggest that enhancement of the recognition of mental disorders and referral practices in primary care represents a significant opportunity to increase appropriate treatment of adolescent mental health disorders.
THE PURPOSE AND STRUCTURE OF THIS BOOK
We have four main objectives with this book. The first is to review and summarize the adolescent literature for the six disorders and for positive youth development. To understand similarities and differences between adults and adolescents with these disorders, an additional objective is to review and briefly summarize the adult literature for the six disorders. On the basis of these literature reviews, each chapter provides recommendations for future research directions that we hope will serve as a template for guiding scientific developments in adolescent mental health. By fostering a specific scientific agenda, our larger objective is to help promote good mental health and positive youth development among adolescents. This book was designed to be similar to a parallel volume addressing adult mental disorders ( A Guide to Treatments That Work, Nathan & Gorman, 2002). Despite many similarities, unique aspects of adolescent mental health necessitated some differences from the Nathan and Gorman ( 2002) volume. The primary differences are the overriding focus on prevention and the theme of positive youth development. In addition, we have included several chapters that address the settings in which adolescent mental health and positive youth development efforts occur, and one discussing an important barrier (i.e., stigma) to enhancing adolescent mental health. A substantial amount of effort went into the planning and creation of this book. The work began with the creation of seven commissions designed to discuss the issues and challenges in adolescent mental health regarding schizophrenia, anxiety disorders, mood disorders, eating disorders, substance abuse, suicide, and positive youth development. Researchers and clinicians from around the world with expertise in these
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areas were recruited for participation. Each commission initiated their work with a meeting during which initial ideas were presented and critiqued. Following this, initial drafts of chapters were prepared. A meeting of participants from all commissions, approaching 100 individuals, was then held in January 2004 to review and critique summaries of the literature and future recommendations. Final chapters were then prepared. Throughout the preparation of the book, there was wide agreement among participants that the six disorders represented a somewhat artificial way to delineate the problems of adolescence. There was recognition that more work was needed on the current DSM system in regard to criteria for diagnosing adolescent disorders. More importantly, however, was the awareness, documented in a number of research studies, that comorbidity was extremely common among adolescent mental disorders, and therefore that the disorders as presently conceived may not “cut nature at the joints.” Furthermore, it may be that what is most relevant to treatment and especially prevention is not the DSM disorders themselves but common pathways to these disorders. However, the six disorders were judged the best way to start the process of understanding adolescent mental health because the empirical literature is oriented around these disorders. The concept of common pathways is addressed within the recommendations of individual chapters, and again in the summary chapter. Each of the disorder-focused chapters follows a common structure. The chapters begin by defining the disorder, including discussion of differences between childhood, adolescent, and adult manifestations of the disorder. Next, a review of epidemiological studies is presented to convey the public health significance of these disorders. This is followed by a review of theory and empirical studies pertaining to etiology and risk factors for the disorder. A broad perspective on etiology and risk factors is taken, so that empirical literature on personality and temperament, cognitive vulnerability, stress, interpersonal relationships, biological factors, genetics, gender, and early life traumas is summarized for each disorder, if relevant. All chapters then discuss comorbidity. After thorough presentation of scientific knowledge concerning the nature of the disorder, each part then addresses intervention. This begins with treatment. A brief review of psychosocial studies in adults, including acute treatment as well as relapse prevention studies, is first given, followed by a more extensive review of adolescent acute-phase and relapse prevention studies. Pharmacological treatment studies in adults and adolescents are then reviewed. The concluding chapter of each part presents the commission's recommendations based on their literature reviews. These recommendations are outlined in terms of a research agenda for the future, summarized in regard to three questions asked separately about the nature of the disorder, treatment of the disorder, and prevention of the disorder: (1) What do we know? (2) What do we not know? (3) What do we urgently need to know? Chapter 26 on positive youth development necessarily deviates from the above structure but retains several of the elements, including parallel recommendations. As mentioned previously, to improve adolescent mental health, some additional issues beyond research on treatment, prevention, or fostering of positive youth development also need to be considered. Four chapters on service delivery systems (mental health, substance abuse, primary care, and schools) provide the larger context needed for understanding how to foster improvements in adolescent mental health and positive youth development. Chapter 27 addresses another significant barrier to improved mental health care: stigma. Penn et al. point out that often adolescents hold stigmatizing attitudes about those with mental disorders. By conveying these attitudes, the likelihood is reduced that those with disorders will seek and continue treatment. This chapter identifies factors that elicit or reinforce stigmatizing attitudes in both adults and youth, including negative labels, lack of contact with those with disorders, and negative portrayals in the mass media. The reduction of stigma is another way to increase the likelihood that adolescents will engage in treatment and prevention programs. The concluding chapter of the book summarizes what has been learned about adolescent disorders, their treatment and prevention, service
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doi:10.1093/9780195173642.003.0001
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